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Using gene editing, neuroscientists develop a new model for autism

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  • Posted by: Admin in Diseases, Medical & Clinical

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By introducing a gene variant associated with autism into monkeys, researchers hope to study treatment options for severe neurodevelopmental disorders. Using the genome-editing system CRISPR, researchers at MIT and in China have engineered macaque monkeys to express a gene mutation linked to autism and other neurodevelopmental disorders in humans. These monkeys show some behavioral traits...

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An escape route for carbon

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  • Posted by: Admin in Environment Articles

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Study shows minerals sequester carbon for thousands of years, which may explain oxygen’s abundance in the atmosphere. As many of us may recall from grade school science class, the Earth’s carbon cycle goes something like this: As plants take up carbon dioxide and convert it into organic carbon, they release oxygen back into the air....

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Getting the oil out of water

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  • Posted by: Admin in Environment Articles

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New technique makes it possible to image the fouling of membranes in 3-D, could lead to better antifouling materials. Oil and water are famously reluctant to mix fully together. But separating them completely — for example, when cleaning up an oil spill or purifying water contaminated through fracking — is a devilishly hard and inefficient...

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Neurons’ “antennae” are unexpectedly active in neural computation

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  • Posted by: Admin in Medical & Clinical

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Tiny, branching extensions called dendrites may be more than just passive information-carriers, study finds. Most neurons have many branching extensions called dendrites that receive input from thousands of other neurons. Dendrites aren’t just passive information-carriers, however. According to a new study from MIT, they appear to play a surprisingly large role in neurons’ ability to...

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Drug makes tumors more susceptible to chemo

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  • Posted by: Admin in Medical & Clinical

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Compound that knocks out a DNA repair pathway enhances cisplatin treatment and helps prevent drug-resistance. Many chemotherapy drugs kill cancer cells by severely damaging their DNA. However, some tumors can withstand this damage by relying on a DNA repair pathway that not only allows them to survive, but also introduces mutations that helps cells become...

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A warning for youth

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  • Posted by: Admin in Medical & Clinical

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Some dietary supplements are linked to severe health events in children, young adults. consumption of dietary supplements sold for weight loss, muscle building, and energy was associated with increased risk for severe medical events in children and young adults compared with consumption of vitamins, according to new research led by Harvard T.H. Chan School of...

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Biotech startup uses nanoparticles to induce immune tolerance

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  • Posted by: Admin in Medical & Clinical

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Selecta Bioscience’s ImmTOR platform could improve gene therapies and prevent some drug side effects. More than 100 approved drugs in the U.S. warn of immune-related side effects on their labels. Countless others never make it onto shelves because of unwanted immune responses that can harm patients and limit the effectiveness of drug candidates. Most gene...

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How we make complex decisions

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  • Posted by: Admin in Medical & Clinical

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Neuroscientists identify a brain circuit that helps break decisions down into smaller pieces. When making a complex decision, we often break the problem down into a series of smaller decisions. For example, when deciding how to treat a patient, a doctor may go through a hierarchy of steps — choosing a diagnostic test, interpreting the...

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Measuring chromosome imbalance could clarify cancer prognosis

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  • Posted by: Admin in Medical & Clinical

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A study of prostate cancer finds “aneuploid” tumors are more likely to be lethal than tumors with normal chromosome numbers. Most human cells have 23 pairs of chromosomes. Any deviation from this number can be fatal for cells, and several genetic disorders, such as Down syndrome, are caused by abnormal numbers of chromosomes. For decades,...

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How a declining environment affects populations

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  • Posted by: Admin in Environment Articles

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Study finds that competition between bacterial species can be upended when conditions deteriorate. Stable ecosystems occasionally experience events that cause widespread death — for example, bacteria in the human gut may be wiped out by antibiotics, or ocean life may be depleted by overfishing. A new study from MIT physicists reveals how these events affect...

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