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New drug combination could be more effective against melanoma

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  • Posted by: Admin in Medical & Clinical

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Chemists discover an unexpected synergy between two types of cancer drugs. A class of cancer drugs called protein kinase inhibitors is one of the most effective treatments for melanoma. However, in many cases, tumors eventually become resistant to the drugs and cause a relapse in the patient. A new study from MIT suggests that combining...

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Measuring cancer cell “fitness” reveals drug susceptibility

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  • Posted by: Admin in Medical & Clinical

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Together, cell growth rate and gene expression shed light on why some tumor cells survive treatment. By studying both the physical and genomic features of cancer cells, MIT researchers have come up with a new way to investigate why some cancer cells survive drug treatment while others succumb. Their new approach, which combines measurements of...

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Potential arthritis treatment prevents cartilage breakdown

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  • Posted by: Admin in Diseases, Medical & Clinical

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Injectable material made of nanoscale particles can deliver arthritis drugs throughout cartilage. Osteoarthritis, a disease that causes severe joint pain, affects more than 20 million people in the United States. Some drug treatments can help alleviate the pain, but there are no treatments that can reverse or slow the cartilage breakdown associated with the disease....

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Biologists discover an unusual hallmark of aging in neurons

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  • Posted by: Admin in Medical & Clinical

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Snippets of RNA that accumulate in brain cells could interfere with normal function. As we age, neurons in our brains can become damaged by free radicals. MIT biologists have now discovered that this type of damage, known as oxidative stress, produces an unusual pileup of short snippets of RNA in some neurons. This RNA buildup,...

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MIT continues progress toward greenhouse gas reductions

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  • Posted by: Admin in Environment Articles

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New generating plant, building retrofits, and progress in metering energy use represent ongoing gains. Despite a challenging year marked by a colder-than-usual winter and the construction of major new campus buildings, MIT has continued its progress toward its declared goal of reducing campus greenhouse gas emissions by 32 percent by the year 2030, as outlined...

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Healthy eating made easy

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  • Posted by: Admin in Diseases, Health, Medical & Clinical

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Startup PlateJoy sends users personalized meal plans to help them achieve health goals. As a busy undergraduate at MIT, Christina Bognet decided she wanted to start eating a healthier diet. She began checking the nutritional content of her food and considering portion sizes. She created grocery lists to minimize food waste and cost, sifting through...

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Explaining the plummeting cost of solar power

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  • Posted by: Admin in Environment Articles

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Researchers uncover the factors that have caused photovoltaic module costs to drop by 99 percent. The dramatic drop in the cost of solar photovoltaic (PV) modules, which has fallen by 99 percent over the last four decades, is often touted as a major success story for renewable energy technology. But one question has never been...

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How the brain switches between different sets of rules

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  • Posted by: Admin in Medical & Clinical

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When you slow down after exiting the highway, or hush your voice in the library, you’re using this brain mechanism. Cognitive flexibility — the brain’s ability to switch between different rules or action plans depending on the context — is key to many of our everyday activities. For example, imagine you’re driving on a highway...

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Newly sequenced genomes of parasitic worms could speed development of new treatments, according to Iowa State University biomedical research

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  • Posted by: Admin in Medical & Clinical

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A schistosome cercaria, which is the form that invades human skin to infect more than 200 million people worldwide. Image courtesy of Sreemoyee Acharya. AMES, Iowa – Parasitic worms pose a major global health threat to both humans and animals, but a major study that sequenced the genomes of scores of worms could lead to...

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Study reveals importance of ‘cryptic connections’ in disease transmission

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  • Posted by: Admin in Environment Articles

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Researchers were able to track cryptic connections between bats by coating individual bats, such as this tri-colored bat, with a dust that is fluorescent under ultraviolet light ("UVF dust"). (Photos by Joseph Hoyt) Innovative study of fungal disease in bats quantifies unseen interactions that play a key role in the spread of disease through populations...

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